B.D. Neon is the leader of the Bad Lads Gang, a group of desert bandits who rob passing sandships. A cruel and narcissistic man, he planned to crash a sandship into a canyon, dooming its entire load of passengers, just to boost his notorious reputation. Trigun, however, avoids the 'dark-skinned villain stereotype' by placing a positive dark-skinned character side-by-side with B.D. Neon. The sandship pilot who honorably refused to crash the ship, saying that he must put the passengers' lives above his own, had the same skin tone as the villain. B.D. Neon callously shoots him dead.

Yet even this villain is not above redemption. Having made a deal with the hero Vash - if he loses the gun duel with Vash, he would let the passengers live - he risked his life to stop the sandship's fatal course. (Vash's victory in the gun duel was not apparent to witnesses, and it was only Neon's honor that prevented him from falsely claiming victory.) Neon, however, cautioned Vash not to misunderstand his gesture as stemming from any goodness of heart - he only saved the ship to keep his promise to Vash.

Meena was once a servant to Prince Soma, the 26th child of the King of Bengal. The young prince, ignored by his parents, loves Meena as a mother figure. Some years after Meena disappears from India, the now grown Prince Soma, together with his butler Agni, goes to England in search of her, assuming that she had been kidnapped by a British nobleman. [Spoilers ahead]

It turns out that Prince Soma's attachment to Meena is one-sided. She has no love for her charge. Unknown to him, Meena willingly left India with the Englishman Harold West, by her own admission "using" West for social climbing. The prince's butler Agni secretly makes contact with Meena to ask her not to divulge her true feelings to the prince so as not to hurt Soma. Meena and Harold use Agni's desire to protect the prince to blackmail Agni into assisting with Harold West's unscrupulous business practices. Agni's efforts are to no avail, because Meena eventually breaks her promise to Agni. Meena tells Soma how much she dislikes him, and how she escaped his service to become a rich man's wife instead of remaining an underling in India's caste-based society. She also expresses her resentment for people of higher social class, such as the Brahmin Agni and the Queen of England. Meena appears in the Curry Contest Arc of Season 1 and also has a small role in Ciel in Wonderland. For more information, see Meena on Kutoshituji Wikia.

Rosny Spanngen is a boy genius who, even when in a coma, could hack into the net and create a complex fictional personality complete with a credible history. This internet persona, thought by the public to be a real person, became the leader of a mysterious cult, gaining thousands of followers with his philosophy. Rosny's aptitude at mind manipulation spells death for the real life bounty hunters who were sent after his fictitious avatar.

Lt Colonel Shadle appears in "Scorching Bonds", the First Negotiation arc (DVDs 1-3). He is a psychopathic military commander obsessed with wiping out his opponents. Pakistani high command transfers Shadle back from Kashmir to fight the rebels that the main character Yugo is negotiating with.

Single-mindedly focused on obliterating the bandit-rebels led by Yusuf Ali Mesa, Lt Colonel Shadle is more than willing to let an entire village of civilians become collateral damage . When his subordinate questions his choice, he angrily and arrogantly overrides all objections.

High-strung and perpetually angry, Shadle tends to go into overkill mode in his reactions to any provocation. He sees his enemies as nothing more than irritating insects to be exterminated.

Udai Taxim, an assassin for the Syndicate, was imprisoned before the beginning of the series. One of the main characters, Jet, believes Udai was responsible for the loss of his arm in an earlier encounter. Jet finally confronts Udai in Session 16: Black Dog Serenade, when the deadly Udai single-handedly kills a group of prison guards in a revolt and takes over a prisoner transport ship. Udai is not a stereotypical brutal criminal with poor impulse control. He is calm, calculated and silent in his deadliness. Jet calls him "old fashioned", meaning his sense of loyalty to the Syndicate was outdated. Sure enough, the Syndicate does not return Udai's loyalty.

This unnamed policeman lives in a nameless Arab country that the protagonist Black Jack was travelling in. The police there are corrupt and morally bankrupt, first trying to force a false confession out of Black Jack, and then casually deciding to "write it up to make it look like he confessed", despite Black Jack's continued pleas of innocence.

This unethical police officer beats up Black Jack while interrogating him, trying to get him to confess to killing a woman. The only witness who claimed Black Jack was the murderer was a drunkard. The officer is convinced Black Jack was the murderer because he carries scalpels despite having no medical license. He orders his men to falsely claim Black Jack confessed after all the beatings proved worthless, with Black Jack still claiming to be innocent.

He only lets Black Jack go when Black Jack's assistant Pinoko brings two witnesses: a Japanese man who spoke with Black Jack in the restaurant when the crime took place and the waitress who served them at the time.

In an episode full of Arabs, there is not one positive Arab character to offset the overwhelmingly negative atmosphere.

Yusuf Ali is a rural leader who consolidated his power by killing all the sheikhs in his area, with one exception. Nicknamed Hell's Hero, the tall large man is notorious for strangling his victims with his bare hands, a fate that befalls a military undercover agent sent to entrap him. Yusuf also strangles one of his own subordinates who failed to control the behavior of a reckless, dishonorable comrade.

Although feared by his men for his explosive violence and quick anger, Yusuf's ultimate goal is to gain political autonomy for the people of his region and protect them from the Pakistani army. To finance that end, he kidnaps a Japanese businessman, leading to the arrival of Yugo the Negotiator, a Japanese private negotiator whose job is to pay the ransom and secure the release of the hostage.

The character of Yusuf Ali moves from being the villain to a sympathetic antihero after the Japanese protagonist Yugo, whom Yusuf had taken captive, continues to reach out to Yusuf even in the face of torture.

Both Yusuf and Yugo find themselves united against the Pakistani army which seeks to destroy Yusuf's rebels without regard for civilians caught in the crossfire. When Yugo makes strategy recommendations and executes plans with the safety of Yusuf's armed followers and unarmed community members as the highest priority, Yusuf's respect for him increases. In turn, Yugo appeals to Yusuf's nobler side, asking him to reverse his slander of an old sheikh who Yusuf defeated years ago.

When pursued by military helicopters, Yusuf courageously stands his ground in the face of incredible odds, making his stand alone with a rocket launcher.

Towards the end of the Pakistani arc, Yusuf transitions into more of a hero character, his difficult decision to lay aside his immediate honor for the longterm survival of his community contrasting sharply against the callous, overbearing attitude of his antagonist Colonel Shadle, the crazed, arrogant military man who cares not how many subordinates and innocents he sacrifices in order to wipe out the rebels.